STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlab_0015Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (455 aa)    
Predicted Functional Partners:
Mlab_0012
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein.
 
 0.999
Mlab_0013
Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
 0.999
Mlab_0014
Coenzyme F420-reducing hydrogenase, delta subunit; TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein.
 
 0.994
Mlab_0242
PFAM: methyl-viologen-reducing hydrogenase, delta subunit.
  
 
 0.942
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
     
 0.926
mer
Methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
 
 0.919
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.915
Mlab_0241
CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.904
Mlab_1211
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein.
 
 
 0.896
Mlab_0239
Heterodisulfide reductase subunit C-like protein.
  
 
 0.877
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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