STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlab_0073Uroporphyrinogen-III synthase-like protein. (231 aa)    
Predicted Functional Partners:
Mlab_0526
TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
  
 0.995
Mlab_0359
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
     
 
0.900
Mlab_0072
PFAM: PUA domain containing protein; pseudouridylate synthase TruB domain protein.
 
    0.896
Mlab_0524
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 
 0.728
cbiMQ
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
  
 0.630
Mlab_1489
PFAM: TrkA-N domain protein; TrkA-C domain protein.
  
    0.600
Mlab_0074
PFAM: protein of unknown function DUF112, transmembrane.
       0.576
Mlab_1235
PFAM: amino acid-binding ACT domain protein.
  
    0.575
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
  
 0.486
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
  
  
 0.423
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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