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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
merMethylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (327 aa)    
Predicted Functional Partners:
Mlab_0012
PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein.
 
 
 0.966
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
   
 
 0.957
Mlab_1553
TIGRFAM: tetrahydromethanopterin S-methyltransferase, MtrH subunit; PFAM: Tetrahydromethanopterin S-methyltransferase, MtrH subunit.
 
  
 0.954
mtrG
Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
    
 0.951
mtrA
Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
    
 0.951
Mlab_0013
Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase, 20 kDa subunit.
  
 
 0.950
mtrE
Tetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
    
 0.928
Mlab_0014
Coenzyme F420-reducing hydrogenase, delta subunit; TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein.
  
 
 0.923
Mlab_0015
Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.919
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.914
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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