Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mlab_0217Methyltransferase; PFAM: putative RNA methylase; methyltransferase small. (200 aa)    
Predicted Functional Partners:
Mlab_0218
Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
 
     0.898
hpt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
       0.883
Mlab_0216
PFAM: major facilitator superfamily MFS_1.
 
    0.815
Mlab_1248
PFAM: RNA polymerase, dimerisation.
  
    0.561
Mlab_0220
Hypothetical protein.
       0.550
ftr
Formylmethanofuran-tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
       0.522
Mlab_0420
PFAM: putative RNA methylase; Methyltransferase type 11.
  
  
 0.495
Mlab_0448
DNA-directed RNA polymerase, subunit M; PFAM: Transcription factor TFIIS.
  
  
 0.478
rpl10e
PFAM: Ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family.
  
    0.469
Mlab_1184
PFAM: Abortive infection protein.
  
    0.451
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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