STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlab_0366TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC). (78 aa)    
Predicted Functional Partners:
Mlab_0364
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
 
 
 0.993
Mlab_1211
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein.
 
 
 0.986
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.905
Mlab_0363
TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase.
       0.779
Mlab_1515
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K.
  
  
 0.760
Mlab_1577
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; Belongs to the carbamoyltransferase HypF family.
 
 
 0.723
Mlab_0500
PFAM: cobalamin synthesis protein, P47K; SMART: AAA ATPase.
  
  
 0.696
Mlab_0015
Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.681
Mlab_0370
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.459
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
       0.448
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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