Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mlab_0502PFAM: protein of unknown function DUF39. (408 aa)    
Predicted Functional Partners:
Mlab_0500
PFAM: cobalamin synthesis protein, P47K; SMART: AAA ATPase.
 
     0.876
Mlab_0503
L-threonine synthase; Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
 
   
 0.872
Mlab_0499
PFAM: ABC transporter related; SMART: AAA ATPase.
 
     0.870
Mlab_0504
Sulfopyruvate decarboxylase subunit beta / sulfopyruvate decarboxylase subunit alpha.
       0.860
Mlab_0501
Fe-S protein-like protein.
       0.852
Mlab_0452
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
 
  
 0.791
Mlab_0453
PFAM: protein of unknown function DUF375; Belongs to the UPF0280 family.
 
   
 0.767
htpX
HtpX-2 peptidase. Metallo peptidase, MEROPS family M48B; PFAM: peptidase M48, Ste24p; Belongs to the peptidase M48B family.
       0.462
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
       0.406
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.