node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mlab_0516 | Mlab_0517 | Mlab_0516 | Mlab_0517 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | 0.837 |
Mlab_0516 | Mlab_0518 | Mlab_0516 | Mlab_0518 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.555 |
Mlab_0516 | Mlab_0519 | Mlab_0516 | Mlab_0519 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | UDP-N-acetylmuramyl pentapeptide synthase-like protein. | 0.564 |
Mlab_0516 | Mlab_0520 | Mlab_0516 | Mlab_0520 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | 0.553 |
Mlab_0516 | Mlab_0522 | Mlab_0516 | Mlab_0522 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | TIGRFAM: siroheme synthase. | 0.545 |
Mlab_0516 | Mlab_0524 | Mlab_0516 | Mlab_0524 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.564 |
Mlab_0516 | Mlab_1313 | Mlab_0516 | Mlab_1313 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein. | 0.477 |
Mlab_0516 | cbiA | Mlab_0516 | Mlab_0521 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.553 |
Mlab_0516 | hemA | Mlab_0516 | Mlab_0523 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.602 |
Mlab_0516 | hemL | Mlab_0516 | Mlab_0525 | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.547 |
Mlab_0517 | Mlab_0516 | Mlab_0517 | Mlab_0516 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 0.837 |
Mlab_0517 | Mlab_0518 | Mlab_0517 | Mlab_0518 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.536 |
Mlab_0517 | Mlab_0519 | Mlab_0517 | Mlab_0519 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | UDP-N-acetylmuramyl pentapeptide synthase-like protein. | 0.536 |
Mlab_0517 | Mlab_0520 | Mlab_0517 | Mlab_0520 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | 0.536 |
Mlab_0517 | Mlab_0522 | Mlab_0517 | Mlab_0522 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | TIGRFAM: siroheme synthase. | 0.536 |
Mlab_0517 | Mlab_0524 | Mlab_0517 | Mlab_0524 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.536 |
Mlab_0517 | Mlab_1313 | Mlab_0517 | Mlab_1313 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | PFAM: HEAT domain containing protein; PBS lyase HEAT domain protein repeat-containing protein. | 0.644 |
Mlab_0517 | cbiA | Mlab_0517 | Mlab_0521 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.536 |
Mlab_0517 | hemA | Mlab_0517 | Mlab_0523 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.536 |
Mlab_0517 | hemL | Mlab_0517 | Mlab_0525 | PFAM: PBS lyase HEAT domain protein repeat-containing protein. | Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.536 |