node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mlab_0518 | Mlab_0520 | Mlab_0518 | Mlab_0520 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | 0.833 |
Mlab_0518 | Mlab_0522 | Mlab_0518 | Mlab_0522 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | TIGRFAM: siroheme synthase. | 0.993 |
Mlab_0518 | Mlab_0524 | Mlab_0518 | Mlab_0524 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.832 |
Mlab_0518 | Mlab_0526 | Mlab_0518 | Mlab_0526 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.958 |
Mlab_0518 | Mlab_1077 | Mlab_0518 | Mlab_1077 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | Cobalt-factor II C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.940 |
Mlab_0518 | Mlab_1078 | Mlab_0518 | Mlab_1078 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | Precorrin-4 C(11)-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.411 |
Mlab_0518 | Mlab_1086 | Mlab_0518 | Mlab_1086 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.902 |
Mlab_0518 | cbiA | Mlab_0518 | Mlab_0521 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.984 |
Mlab_0518 | hemA | Mlab_0518 | Mlab_0523 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.868 |
Mlab_0518 | hemL | Mlab_0518 | Mlab_0525 | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.831 |
Mlab_0520 | Mlab_0518 | Mlab_0520 | Mlab_0518 | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.833 |
Mlab_0520 | Mlab_0522 | Mlab_0520 | Mlab_0522 | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | TIGRFAM: siroheme synthase. | 0.805 |
Mlab_0520 | Mlab_0524 | Mlab_0520 | Mlab_0524 | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.794 |
Mlab_0520 | Mlab_0526 | Mlab_0520 | Mlab_0526 | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.911 |
Mlab_0520 | cbiA | Mlab_0520 | Mlab_0521 | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. | 0.985 |
Mlab_0520 | hemA | Mlab_0520 | Mlab_0523 | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.798 |
Mlab_0520 | hemL | Mlab_0520 | Mlab_0525 | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | Glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.796 |
Mlab_0522 | Mlab_0518 | Mlab_0522 | Mlab_0518 | TIGRFAM: siroheme synthase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. | 0.993 |
Mlab_0522 | Mlab_0520 | Mlab_0522 | Mlab_0520 | TIGRFAM: siroheme synthase. | Nitrogenase molybdenum-iron protein alpha and beta chains-like protein. | 0.805 |
Mlab_0522 | Mlab_0524 | Mlab_0522 | Mlab_0524 | TIGRFAM: siroheme synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.850 |