STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlab_0772PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (198 aa)    
Predicted Functional Partners:
Mlab_0153
TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.
  
  
 0.937
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
     
 0.916
pyrD
Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
     
 0.911
Mlab_0594
Dihydroorotate oxidase B, electron transfer subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein.
     
  0.900
Mlab_0775
TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family.
    
  0.866
Mlab_1576
PFAM: Helix-turn-helix, type 11 domain protein; SMART: regulatory protein, Crp.
  
     0.647
Mlab_1405
PFAM: PilT protein domain protein; SMART: Nucleotide binding protein, PINc.
  
     0.606
rpl40e
PFAM: Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.572
Mlab_0924
Nmd3; PFAM: NMD3.
  
     0.569
Mlab_1369
PFAM: aminoacyl-tRNA synthetase, class Ib; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.569
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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