node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mlab_0206 | Mlab_0776 | Mlab_0206 | Mlab_0776 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | TIGRFAM: peptidase S16, Lon-like protease; PFAM: magnesium chelatase, ChlI subunit; peptidase S16, lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 0.723 |
Mlab_0206 | dnaJ | Mlab_0206 | Mlab_0942 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.727 |
Mlab_0206 | dnaK | Mlab_0206 | Mlab_0943 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Chaperone protein DnaK; Acts as a chaperone. | 0.960 |
Mlab_0206 | fusA | Mlab_0206 | Mlab_1613 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.697 |
Mlab_0206 | grpE | Mlab_0206 | Mlab_0944 | TIGRFAM: thermosome; PFAM: chaperonin Cpn60/TCP-1. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.961 |
Mlab_0407 | Mlab_0776 | Mlab_0407 | Mlab_0776 | Hypothetical protein. | TIGRFAM: peptidase S16, Lon-like protease; PFAM: magnesium chelatase, ChlI subunit; peptidase S16, lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 0.702 |
Mlab_0407 | dnaJ | Mlab_0407 | Mlab_0942 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.494 |
Mlab_0407 | dnaK | Mlab_0407 | Mlab_0943 | Hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone. | 0.777 |
Mlab_0407 | fusA | Mlab_0407 | Mlab_1613 | Hypothetical protein. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.438 |
Mlab_0407 | rpl40e | Mlab_0407 | Mlab_0651 | Hypothetical protein. | PFAM: Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.977 |
Mlab_0771 | Mlab_0776 | Mlab_0771 | Mlab_0776 | PFAM: chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family. | TIGRFAM: peptidase S16, Lon-like protease; PFAM: magnesium chelatase, ChlI subunit; peptidase S16, lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 0.687 |
Mlab_0771 | dnaJ | Mlab_0771 | Mlab_0942 | PFAM: chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.727 |
Mlab_0771 | dnaK | Mlab_0771 | Mlab_0943 | PFAM: chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family. | Chaperone protein DnaK; Acts as a chaperone. | 0.957 |
Mlab_0771 | fusA | Mlab_0771 | Mlab_1613 | PFAM: chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family. | Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] | 0.672 |
Mlab_0771 | grpE | Mlab_0771 | Mlab_0944 | PFAM: chaperonin Cpn60/TCP-1; Belongs to the TCP-1 chaperonin family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.955 |
Mlab_0774 | Mlab_0775 | Mlab_0774 | Mlab_0775 | Nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein. | TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.861 |
Mlab_0774 | Mlab_0776 | Mlab_0774 | Mlab_0776 | Nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein. | TIGRFAM: peptidase S16, Lon-like protease; PFAM: magnesium chelatase, ChlI subunit; peptidase S16, lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 0.724 |
Mlab_0774 | rpl40e | Mlab_0774 | Mlab_0651 | Nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein. | PFAM: Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.852 |
Mlab_0775 | Mlab_0774 | Mlab_0775 | Mlab_0774 | TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | Nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein. | 0.861 |
Mlab_0775 | Mlab_0776 | Mlab_0775 | Mlab_0776 | TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family. | TIGRFAM: peptidase S16, Lon-like protease; PFAM: magnesium chelatase, ChlI subunit; peptidase S16, lon domain protein; SMART: AAA ATPase; Belongs to the peptidase S16 family. | 0.645 |