| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mlab_0804 | Mlab_0922 | Mlab_0804 | Mlab_0922 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein. | 0.717 |
| Mlab_0804 | Mlab_1175 | Mlab_0804 | Mlab_1175 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp. | 0.599 |
| Mlab_0804 | Mlab_1486 | Mlab_0804 | Mlab_1486 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein. | 0.585 |
| Mlab_0804 | aspS | Mlab_0804 | Mlab_0039 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). | 0.595 |
| Mlab_0804 | carS | Mlab_0804 | Mlab_0318 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.581 |
| Mlab_0804 | fen | Mlab_0804 | Mlab_0356 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.561 |
| Mlab_0804 | infB | Mlab_0804 | Mlab_1520 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | Translation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.623 |
| Mlab_0804 | rpl4 | Mlab_0804 | Mlab_0082 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel. | 0.574 |
| Mlab_0804 | rpoD | Mlab_0804 | Mlab_1244 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | DNA-directed RNA polymerase, subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.606 |
| Mlab_0804 | truD | Mlab_0804 | Mlab_0803 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | tRNA pseudouridine synthase D, TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.904 |
| Mlab_0922 | Mlab_0804 | Mlab_0922 | Mlab_0804 | TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein. | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | 0.717 |
| Mlab_1175 | Mlab_0804 | Mlab_1175 | Mlab_0804 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp. | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | 0.599 |
| Mlab_1175 | truD | Mlab_1175 | Mlab_0803 | TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp. | tRNA pseudouridine synthase D, TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.487 |
| Mlab_1486 | Mlab_0804 | Mlab_1486 | Mlab_0804 | TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein. | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | 0.585 |
| aspS | Mlab_0804 | Mlab_0039 | Mlab_0804 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | 0.595 |
| aspS | fen | Mlab_0039 | Mlab_0356 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.609 |
| aspS | infB | Mlab_0039 | Mlab_1520 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). | Translation initiation factor eaIF-5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.531 |
| aspS | truD | Mlab_0039 | Mlab_0803 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). | tRNA pseudouridine synthase D, TruD; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.513 |
| carS | Mlab_0804 | Mlab_0318 | Mlab_0804 | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | 0.581 |
| fen | Mlab_0804 | Mlab_0356 | Mlab_0804 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099. | 0.561 |