node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mlab_0182 | dadD | Mlab_0182 | Mlab_1054 | PFAM: Xanthine/uracil/vitamin C permease. | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | 0.508 |
Mlab_1052 | Mlab_1053 | Mlab_1052 | Mlab_1053 | PFAM: cytochrome c biogenesis protein, transmembrane region. | PFAM: purine phosphorylase, family 2. | 0.596 |
Mlab_1052 | Mlab_1055 | Mlab_1052 | Mlab_1055 | PFAM: cytochrome c biogenesis protein, transmembrane region. | SMART: transglutaminase domain protein. | 0.499 |
Mlab_1052 | dadD | Mlab_1052 | Mlab_1054 | PFAM: cytochrome c biogenesis protein, transmembrane region. | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | 0.639 |
Mlab_1053 | Mlab_1052 | Mlab_1053 | Mlab_1052 | PFAM: purine phosphorylase, family 2. | PFAM: cytochrome c biogenesis protein, transmembrane region. | 0.596 |
Mlab_1053 | Mlab_1055 | Mlab_1053 | Mlab_1055 | PFAM: purine phosphorylase, family 2. | SMART: transglutaminase domain protein. | 0.605 |
Mlab_1053 | Mlab_1056 | Mlab_1053 | Mlab_1056 | PFAM: purine phosphorylase, family 2. | PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein. | 0.461 |
Mlab_1053 | Mlab_1411 | Mlab_1053 | Mlab_1411 | PFAM: purine phosphorylase, family 2. | TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Acetohydroxy acid isomeroreductase, catalytic domain protein; Belongs to the adenosylhomocysteinase family. | 0.495 |
Mlab_1053 | dadD | Mlab_1053 | Mlab_1054 | PFAM: purine phosphorylase, family 2. | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | 0.994 |
Mlab_1055 | Mlab_1052 | Mlab_1055 | Mlab_1052 | SMART: transglutaminase domain protein. | PFAM: cytochrome c biogenesis protein, transmembrane region. | 0.499 |
Mlab_1055 | Mlab_1053 | Mlab_1055 | Mlab_1053 | SMART: transglutaminase domain protein. | PFAM: purine phosphorylase, family 2. | 0.605 |
Mlab_1055 | Mlab_1056 | Mlab_1055 | Mlab_1056 | SMART: transglutaminase domain protein. | PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein. | 0.593 |
Mlab_1055 | dadD | Mlab_1055 | Mlab_1054 | SMART: transglutaminase domain protein. | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | 0.604 |
Mlab_1056 | Mlab_1053 | Mlab_1056 | Mlab_1053 | PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein. | PFAM: purine phosphorylase, family 2. | 0.461 |
Mlab_1056 | Mlab_1055 | Mlab_1056 | Mlab_1055 | PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein. | SMART: transglutaminase domain protein. | 0.593 |
Mlab_1056 | dadD | Mlab_1056 | Mlab_1054 | PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein. | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | 0.459 |
Mlab_1411 | Mlab_1053 | Mlab_1411 | Mlab_1053 | TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Acetohydroxy acid isomeroreductase, catalytic domain protein; Belongs to the adenosylhomocysteinase family. | PFAM: purine phosphorylase, family 2. | 0.495 |
Mlab_1411 | dadD | Mlab_1411 | Mlab_1054 | TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Acetohydroxy acid isomeroreductase, catalytic domain protein; Belongs to the adenosylhomocysteinase family. | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | 0.444 |
Mlab_1703 | dadD | Mlab_1703 | Mlab_1054 | PFAM: band 7 protein. | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | 0.726 |
dadD | Mlab_0182 | Mlab_1054 | Mlab_0182 | Amidohydrolase; Catalyzes the deamination of three SAM-derived enzymatic products, namely 5'-deoxyadenosine, S-adenosyl-L-homocysteine, and 5'- methylthioadenosine, to produce the inosine analogs. Can also deaminate adenosine. The preferred substrate for this enzyme is 5'- deoxyadenosine, but all these substrates are efficiently deaminated. Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. May also be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose m [...] | PFAM: Xanthine/uracil/vitamin C permease. | 0.508 |