STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlab_1086PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein. (135 aa)    
Predicted Functional Partners:
Mlab_0522
TIGRFAM: siroheme synthase.
 
 
 0.972
Mlab_1077
Cobalt-factor II C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.939
cbiA
Cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
    
 0.925
Mlab_0518
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein.
  
  
 
0.902
Mlab_0526
TIGRFAM: porphobilinogen deaminase; uroporphyrin-III C-methyltransferase; PFAM: Porphobilinogen deaminase; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
  
  
 0.824
cbiM2
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
  
 0.641
cbiN
Cobalt transport protein CbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
     
 0.629
Mlab_1087
PFAM: protein of unknown function UPF0066.
       0.619
Mlab_1089
PFAM: transport system permease protein; ABC-3 protein.
  
    0.571
cbiMQ
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
  
 0.570
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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