STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mlab_1561Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (568 aa)    
Predicted Functional Partners:
Mlab_1562
PFAM: Methyl-coenzyme M reductase, gamma subunit.
  
 0.998
Mlab_1565
PFAM: Methyl-coenzyme M reductase, beta subunit.
  
 0.996
Mlab_1067
PFAM: Methyl-coenzyme M reductase, gamma subunit.
  
 0.992
Mlab_1563
PFAM: Methyl-coenzyme M reductase operon protein C.
  
 
 0.992
Mlab_1564
PFAM: Methyl-coenzyme M reductase, protein D.
  
 
 0.992
Mlab_1066
Coenzyme-B sulfoethylthiotransferase; PFAM: Methyl-coenzyme M reductase, beta subunit.
  
 0.991
Mlab_0555
PFAM: ABC transporter related; SMART: AAA ATPase.
    
 0.910
Mlab_0729
PFAM: ABC transporter related; SMART: AAA ATPase.
    
 0.910
Mlab_1068
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
     
 
0.900
Mlab_1316
PFAM: Radical SAM domain protein; protein of unknown function DUF512.
   
 
 0.822
Your Current Organism:
Methanocorpusculum labreanum
NCBI taxonomy Id: 410358
Other names: M. labreanum Z, Methanocorpusculum labreanum Z, Methanocorpusculum labreanum str. Z, Methanocorpusculum labreanum strain Z
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