STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_0010Putative circadian clock protein, KaiC; PFAM: KaiC domain protein; KEGG: pai:PAE0729 hypothetical protein. (257 aa)    
Predicted Functional Partners:
Pcal_1347
SMART: AAA ATPase; KEGG: pai:PAE0320 P.aerophilum family 417, putative ATP binding.
  
     0.691
Pcal_0011
TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: pai:PAE0794 cytidine deaminase.
       0.640
Pcal_0223
SMART: AAA ATPase; KEGG: pai:PAE0320 P.aerophilum family 417, putative ATP binding.
  
     0.543
Pcal_0009
KEGG: pai:PAE0730 hypothetical protein.
       0.507
Pcal_0008
PFAM: regulatory protein, Crp; KEGG: pai:PAE0731 transcriptional regulatory protein, conjectural.
       0.478
Pcal_0012
KEGG: pai:PAE0796 hypothetical protein.
       0.478
Pcal_0013
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pai:PAE0797 short chain dehydrogenase.
       0.448
rfcL
Transcriptional regulator, Fis family; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
 
     0.424
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.