STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_0215KEGG: pai:PAE0329 putative thiamine transport system permease protein. (474 aa)    
Predicted Functional Partners:
Pcal_0214
TIGRFAM: ABC transporter, periplasmic binding protein, thiB subfamily; PFAM: extracellular solute-binding protein, family 1; KEGG: pai:PAE0331 thiamine-binding periplasmic protein.
 
 
 0.992
Pcal_0216
Carbohydrate ABC transporter ATP-binding protein, CUT1 family; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pai:PAE0328 thiamine transport ATP-binding protein; TC 3.A.1.1.-.
 
 
 0.857
Pcal_0248
PFAM: extracellular solute-binding protein, family 1; KEGG: pai:PAE0061 extracellular solute binding protein, conjectural.
  
  
 0.804
Pcal_0650
KEGG: pai:PAE3657 hypothetical protein.
  
  
 0.804
Pcal_0102
KEGG: pai:PAE0934 hypothetical protein.
   
  
 0.595
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
       0.542
Pcal_1518
PFAM: transport system permease protein; KEGG: pai:PAE0366 iron (III) dicitrate transport system, permease protein, putative.
   
  
 0.540
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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