STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_0737KEGG: pai:PAE1166 hypothetical protein. (238 aa)    
Predicted Functional Partners:
Pcal_0738
PFAM: Radical SAM domain protein; KEGG: pai:PAE1163 hypothetical protein.
 
   
 0.859
mqnD
Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
   
 0.737
Pcal_1703
TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: pai:PAE2375 4-hydroxybenzoate octaprenyltransferase.
 
   
 0.614
mqnC
Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.606
Pcal_2136
Molybdopterin synthase subunit MoaE / molybdopterin synthase subunit MoaD; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: pai:PAE0727 molybdenum cofactor biosynthesis protein D/E.
 
     0.596
ubiX
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
     
 0.472
Pcal_0739
Hypothetical protein; KEGG: pai:PAE1943 paREP5.
       0.450
Pcal_1118
PFAM: Quinolinate phosphoribosyl transferase; KEGG: pai:PAE2990 nicotinate phosphoribosyltransferase.
 
     0.424
Pcal_0497
TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: pai:PAE1844 3-octaprenyl-4-hydroxybenzoate carboxy-lyase.
 
   
 0.410
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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