STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_0771TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein; KEGG: pai:PAE1204 pantothenate metabolism flavoprotein (dfp). (408 aa)    
Predicted Functional Partners:
Pcal_0384
Pantothenate synthetase; PFAM: Protein of unknown function DUF137; KEGG: pai:PAE3406 hypothetical protein.
 
  
 0.957
Pcal_0071
TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: pai:PAE0887 pantetheine-phosphate adenylyltransferase.
    
 0.915
Pcal_0962
PFAM: aminotransferase, class I and II; KEGG: pai:PAE2251 aspartate aminotransferase (aspC), conjectural.
 
  0.901
Pcal_0914
L-aspartate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: pai:PAE1964 aspartate aminotransferase, conjectural.
 
  0.876
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
       0.786
Pcal_0773
PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; phospholipase/Carboxylesterase; WD40 domain protein beta Propeller; KEGG: pai:PAE1189 acylamino-acid-releasing enzyme, conjectural.
       0.762
Pcal_1024
Bis(5'nucleosyl)-tetraphosphatase, ApaH; PFAM: metallophosphoesterase; SMART: serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase; KEGG: pai:PAE2004 serine/threonine specific protein phosphatase.
   
 
 0.751
Pcal_0677
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: pai:PAE1056 ThiF/MoeB/HesA family protein.
 
 
 0.633
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
  
 0.626
Pcal_0382
PFAM: GHMP kinase; KEGG: pai:PAE3407 hypothetical protein.
 
   
 0.575
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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