STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
Pcal_0803Serine O-acetyltransferase; KEGG: pai:PAE1472 acetyl/acyl transferase related protein. (212 aa)    
Predicted Functional Partners:
Pcal_0058
PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: pai:PAE0870 conserved NAD/P oxidoreductase.
  
 0.973
Pcal_0404
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: pai:PAE2053 pleiotropic regulatory protein, conjectural; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.922
Pcal_1766
PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: pai:PAE3281 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase, conjectural; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.696
Pcal_0675
Cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: pai:PAE1051 cysteine synthase.
   
 0.684
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.562
Pcal_0802
KEGG: pai:PAE1453 hypothetical protein.
       0.556
Pcal_0801
KEGG: pai:PAE1451 hypothetical protein.
       0.530
Pcal_1136
PFAM: protein of unknown function DUF354; KEGG: pai:PAE2970 hypothetical protein.
 
    0.491
Pcal_1570
KEGG: sto:ST1045 hypothetical protein.
  
  
 0.421
Pcal_2138
Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.421
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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