STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Pcal_0804Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: pai:PAE1499 aconitate hydratase. (873 aa)    
Predicted Functional Partners:
Pcal_0154
KEGG: pai:PAE3584 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.998
Pcal_0563
KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.998
Pcal_0579
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pai:PAE1651 isocitrate dehydrogenase.
  
 0.997
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.971
prpB
2,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 0.969
Pcal_0625
2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; KEGG: pai:PAE1717 propionate catabolism protein prpD.
  
 
 0.945
Pcal_1605
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pai:PAE1995 3-isopropylmalate dehydrogenase.
  
 0.941
Pcal_1387
PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent.
  
 0.922
Pcal_1515
PFAM: peptidase M16 domain protein; KEGG: pai:PAE0368 protease.
  
 0.886
Pcal_0229
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.884
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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