STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_0949Predicted aconitase subunit 1; PFAM: protein of unknown function DUF521; KEGG: pai:PAE2233 hypothetical protein. (368 aa)    
Predicted Functional Partners:
Pcal_0950
Predicted aconitase subunit 2; KEGG: pai:PAE2234 hypothetical protein.
 
 0.991
Pcal_0948
TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: pai:PAE2232 hypothetical protein.
 
     0.875
albA
Nucleoid protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family.
 
     0.670
Pcal_0579
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: pai:PAE1651 isocitrate dehydrogenase.
     
 0.593
Pcal_0154
KEGG: pai:PAE3584 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
    
 0.569
Pcal_0563
KEGG: pai:PAE1689 citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
    
 0.569
Pcal_0804
Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: pai:PAE1499 aconitate hydratase.
     
 0.551
Pcal_1764
Protein of unknown function DUF359; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
     0.510
rpl31e
PFAM: Ribosomal protein L31e; KEGG: pai:PAE3095 ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family.
  
     0.507
Pcal_0945
KEGG: pai:PAE2224 hypothetical protein.
       0.448
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.