STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1010PFAM: peptidase M24; KEGG: pai:PAE2025 xaa-Pro dipeptidase, putative. (322 aa)    
Predicted Functional Partners:
Pcal_1011
KEGG: pai:PAE2024 hypothetical protein.
  
 
 0.802
Pcal_1012
Transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein; KEGG: pai:PAE2022 conserved (helix-turn-helix protein, CopG family).
       0.777
eIF5A
Translation initiation factor 5A precursor (eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 0.579
Pcal_1013
TIGRFAM: riboflavin synthase; KEGG: pai:PAE2021 riboflavin synthase beta chain.
       0.566
Pcal_0881
PFAM: NADP oxidoreductase, coenzyme F420-dependent; KEGG: pai:PAE1917 pyrroline-5-carboxylate reductase.
 
 
 0.494
map
Methionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
 
  
 0.479
Pcal_1127
KEGG: pai:PAE2980 ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; Belongs to the ribose-phosphate pyrophosphokinase family.
 
 
   0.464
Pcal_1387
PFAM: aldehyde dehydrogenase; KEGG: sto:ST0064 glyceraldehyde-3-phosphate dehydrogenase, NADP dependent.
 
 
 0.464
Pcal_0606
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: sugar isomerase (SIS); KEGG: pai:PAE1610 hypothetical protein.
 
  
 0.461
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 
 0.454
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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