STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
Pcal_1032Glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. Has a broad hexose specificity, and in addition to glucose, which shows the highest catalytic efficiency, it can also phosphorylate fructose, mannose, galactose and sorbitol. Can also use CTP, GTP or UTP as phosphoryl donor. (296 aa)    
Predicted Functional Partners:
Pcal_0606
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: sugar isomerase (SIS); KEGG: pai:PAE1610 hypothetical protein.
 
 
 0.962
Pcal_0544
PFAM: Myo-inositol-1-phosphate synthase; Myo-inositol-1-phosphate synthase, GAPDH domain protein; KEGG: pai:PAE1761 myo-inositol-1-phosphate synthase.
     
 0.903
fbp
Fructose-bisphosphate aldolase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.851
Pcal_1233
Glycerate 2-kinase; PFAM: MOFRL domain protein; KEGG: pai:PAE1309 hypothetical protein.
    
  0.829
Pcal_0893
PFAM: Transketolase domain protein; KEGG: pai:PAE1929 transketolase (N terminal section).
    
 0.817
Pcal_0786
KEGG: pai:PAE1231 deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase.
    
  0.816
Pcal_0894
Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein; KEGG: pai:PAE1927 transketolase (C terminal section).
    
 0.814
Pcal_2157
Alpha-phosphoglucomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pai:PAE0764 phosphomannomutase (pmm); Belongs to the phosphohexose mutase family.
  
 
 0.785
Pcal_0768
KEGG: pai:PAE1209 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77.
   
 0.755
Pcal_0350
PFAM: dihydrodipicolinate synthetase; KEGG: pai:PAE2915 dihydrodipicolinate synthase.
  
  
 0.699
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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