STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1069KEGG: pai:PAE2154 hypothetical protein. (392 aa)    
Predicted Functional Partners:
Pcal_1070
PFAM: protein of unknown function DUF87; SMART: AAA ATPase; KEGG: pai:PAE2155 conserved within P.aerophilum.
       0.845
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
       0.658
Pcal_1072
PFAM: class II aldolase/adducin family protein; KEGG: pai:PAE2158 fuculose-1-phosphate aldolase.
       0.658
Pcal_1073
2,3-di-O-geranylgeranylglyceryl phosphate reductase; TIGRFAM: geranylgeranyl reductase; PFAM: FAD dependent oxidoreductase; KEGG: pai:PAE2159 hypothetical protein.
       0.658
Pcal_1074
PFAM: beta-lactamase domain protein; KEGG: pai:PAE2160 hypothetical metal-dependent hydrolase; Belongs to the UPF0173 family.
       0.577
Pcal_1075
KEGG: pai:PAE2161 hypothetical protein.
       0.432
hjc
Holliday junction resolvase; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family.
       0.405
Pcal_1077
KEGG: pai:PAE2163 hypothetical protein.
       0.405
tbp
TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
       0.405
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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