STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1211KEGG: pai:PAE2458 tryptophan synthase alpha subunit; TIGRFAM: tryptophan synthase, alpha subunit; PFAM: tryptophan synthase, alpha chain. (240 aa)    
Predicted Functional Partners:
Pcal_1213
PFAM: Indole-3-glycerol phosphate synthase; KEGG: pai:PAE0570 indole-3-glycerol-phosphate synthase.
 
 
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
  
 0.998
Pcal_1210
Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pai:PAE2459 anthranilate synthase component II.
 
  
 0.995
trpF
PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pai:PAE2499 phosphoribosyl anthranilate isomerase; Belongs to the TrpF family.
 
  
 0.991
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 0.982
trpB-2
Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 0.978
Pcal_1209
PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: pai:PAE2460 anthranilate synthase component I.
 
  
 0.970
Pcal_1660
L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; amino acid-binding ACT domain protein; KEGG: pai:PAE2316 threonine dehydratase.
  
 
 0.937
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.930
Pcal_1016
Phosphoserine phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pai:PAE2017 phosphoserine phosphatase.
  
 
 0.913
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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