STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1284TIGRFAM: CRISPR-associated protein, Crm2 family; KEGG: sso:SSO1729 hypothetical protein. (874 aa)    
Predicted Functional Partners:
Pcal_1285
TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; KEGG: pfu:PF1126 hypothetical protein.
 
 
 
 0.967
Pcal_0273
TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; KEGG: sso:SSO1987 hypothetical protein.
 
 
 
 0.929
Pcal_0276
TIGRFAM: CRISPR-associated RAMP protein, Cmr6 family; PFAM: protein of unknown function DUF324; KEGG: sso:SSO1990 hypothetical protein.
 
 
 
 0.929
Pcal_1287
TIGRFAM: CRISPR-associated RAMP protein, Cmr6 family; PFAM: protein of unknown function DUF324; KEGG: sto:ST1978 hypothetical protein.
 
 
 
 0.928
Pcal_0274
TIGRFAM: CRISPR-associated protein, Cmr5 family.
   
 
 0.838
Pcal_1283
KEGG: pai:PAE0119 hypothetical protein.
     
 0.820
Pcal_0271
CRISPR-associated protein, Cmr3 family.
   
 
 0.791
Pcal_1282
KEGG: pai:PAE0116 hypothetical protein.
       0.778
cas1
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.620
Pcal_1268
CRISPR-associated helicase, Cas3 family; KEGG: sto:ST2639 hypothetical protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: DEAD-like helicases-like.
 
  
 0.576
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.