STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1368Protein of unknown function DUF650, N-terminal domain protein; Involved in DNA damage repair. (395 aa)    
Predicted Functional Partners:
Pcal_1367
PFAM: periplasmic solute binding protein; KEGG: pai:PAE0564 putative zinc / manganese transport system substrate-binding protein.
       0.778
Pcal_1369
PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: formate dehydrogenase.
       0.682
Pcal_1370
PFAM: Rieske [2Fe-2S] domain protein; KEGG: hypothetical protein.
       0.682
Pcal_0944
Phosphate uptake regulator, PhoU; PFAM: SpoVT/AbrB domain protein; PhoU family protein; KEGG: pai:PAE2220 hypothetical protein.
 
     0.663
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.659
Pcal_1015
Phosphate uptake regulator, PhoU; PFAM: SpoVT/AbrB domain protein; PhoU family protein; KEGG: pai:PAE2019 hypothetical protein.
 
     0.627
Pcal_0002
Cell division control protein 6; Involved in regulation of DNA replication.
  
     0.585
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
     0.583
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
     0.579
Pcal_1883
KEGG: pai:PAE1399 hypothetical protein.
  
     0.577
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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