STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1402TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: pai:PAE2649 pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). (443 aa)    
Predicted Functional Partners:
Pcal_1403
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: pai:PAE2648 pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).
 0.999
Pcal_1405
PFAM: dehydrogenase, E1 component; KEGG: pai:PAE2644 pyruvate dehydrogenase E1 alpha subunit.
 
 0.999
Pcal_1404
PFAM: Transketolase, central region; Transketolase domain protein; KEGG: pai:PAE2646 pyruvate dehydrogenase E1 beta subunit.
 
 0.997
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.939
Pcal_1697
TIGRFAM: Glutaredoxin-like domain protein; PFAM: Thioredoxin domain; KEGG: pai:PAE2366 glutaredoxin-like protein.
  
 0.920
Pcal_1702
PFAM: Thioredoxin domain; KEGG: thioredoxin.
  
 0.920
Pcal_0107
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE0938 2-oxoacid ferredoxin oxidoreductase beta subunit.
    
 0.913
Pcal_0560
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: pai:PAE1558 2-oxoacid ferredoxin oxidoreductase beta subunit.
    
 0.913
Pcal_0108
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE0939 2-oxoacid ferredoxin oxidoreductase alpha subunit.
  
 
 0.910
Pcal_0561
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pai:PAE1559 2-oxoacid ferredoxin oxidoreductase alpha subunit.
  
 
 0.910
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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