STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_1451PFAM: SirA family protein; KEGG: pai:PAE2601 hypothetical protein. (75 aa)    
Predicted Functional Partners:
Pcal_1450
KEGG: pai:PAE2600 hypothetical protein.
       0.773
Pcal_1454
KEGG: pai:PAE2712 hypothetical protein.
 
  
 0.728
Pcal_1453
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pai:PAE2834 hypothetical protein.
     
 0.671
Pcal_1452
PFAM: protein of unknown function DUF1641; KEGG: pai:PAE2833 hypothetical protein.
       0.652
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.638
Pcal_1478
PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: pai:PAE2635 hypothetical protein.
  
  
 0.621
Pcal_1449
KEGG: pai:PAE2599 hypothetical protein.
       0.553
Pcal_1710
TIGRFAM: siroheme synthase; KEGG: pai:PAE0585 siroheme synthesis protein, conjectural.
    
  0.542
Pcal_2136
Molybdopterin synthase subunit MoaE / molybdopterin synthase subunit MoaD; TIGRFAM: MoaD family protein; PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: pai:PAE0727 molybdenum cofactor biosynthesis protein D/E.
   
 
 0.536
Pcal_0387
PFAM: SirA family protein; KEGG: pai:PAE2711a hypothetical protein.
     
 
0.499
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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