Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Pcal_2016PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: pai:PAE3631 NAD dependent epimerase/dehydratase, putative. (306 aa)    
Predicted Functional Partners:
rps12
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.
  
 0.940
rps3
SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.935
rps19
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 0.932
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: pai:PAE3472 ribosomal protein S3; Belongs to the eukaryotic ribosomal protein eS1 family.
   
 0.928
rps24e
PFAM: Ribosomal protein S24e; KEGG: pai:PAE2434 ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.
   
 0.926
rps14
SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles.
  
 0.925
rps17
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 0.923
rps5
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy.
   
 0.923
rps2
PFAM: ribosomal protein S2; KEGG: pai:PAE0817 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 0.921
rps19e
SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
   
  0.921
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
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