STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_2121PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE0707 hypothetical protein. (565 aa)    
Predicted Functional Partners:
Pcal_0964
PFAM: Radical SAM domain protein; KEGG: pai:PAE2255 hypothetical protein.
 
     0.625
Pcal_2120
KEGG: pai:PAE0705 hypothetical protein.
       0.560
Pcal_0589
SMART: helix-turn-helix domain protein; KEGG: pai:PAE1638 putative transcriptional regulator.
  
     0.553
Pcal_0577
NMD3; PFAM: NMD3; KEGG: pai:PAE1653 hypothetical protein.
  
     0.547
aspS
aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
       0.525
Pcal_0405
PFAM: TatD-related deoxyribonuclease; KEGG: pai:PAE2050 hypothetical protein.
  
     0.510
Pcal_0123
KEGG: pai:PAE0967 hypothetical protein.
  
     0.454
Pcal_1596
Phosphoadenosine phosphosulfate reductase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; phosphoadenosine phosphosulfate reductase; KEGG: pai:PAE1989 hypothetical protein.
  
     0.432
Pcal_0596
PFAM: regulatory protein, MerR; helix-turn-helix domain protein; Resolvase helix-turn-helix domain protein; KEGG: pai:PAE1627 putative transcriptional regulator.
  
     0.422
Pcal_1670
PFAM: protein of unknown function DUF115; KEGG: pai:PAE2328 hypothetical protein.
 
     0.413
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.