Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Pcal_2139PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: pai:PAE0791 hypothetical protein. (197 aa)    
Predicted Functional Partners:
Pcal_2138
Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.671
rpl37e
LSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
       0.625
Pcal_2141
Small nuclear ribonucleoprotein, LSM family; PFAM: Like-Sm ribonucleoprotein, core; SMART: Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core; KEGG: pai:PAE0790 small nuclear ribonucleoprotein homolog (Sm-like).
       0.625
Pcal_2137
KEGG: pai:PAE0728 hypothetical protein.
       0.566
Pcal_2142
KEGG: pai:PAE0789 hypothetical protein.
       0.457
Pcal_2143
Hypothetical protein.
       0.457
Your Current Organism:
Pyrobaculum calidifontis
NCBI taxonomy Id: 410359
Other names: P. calidifontis JCM 11548, Pyrobaculum calidifontis JCM 11548, Pyrobaculum calidifontis VA1, Pyrobaculum calidifontis str. JCM 11548, Pyrobaculum calidifontis strain JCM 11548
Server load: low (12%) [HD]