STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2I2FMR4Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (504 aa)    
Predicted Functional Partners:
A0A2I2EZB7
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.926
A0A2I2F696
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
    
 0.924
A0A2I2F030
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.922
A0A2I2F9H2
Putative acetyl-CoA-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.922
A0A2I2F376
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
A0A2I2F7R7
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.921
A0A2I2F8Q1
3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.916
A0A2I2F762
3-ketoacyl-CoA ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.908
A0A2I2F9H7
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.908
A0A2I2F4H3
Acetoacetyl-CoA synthase.
  
 
 0.907
Your Current Organism:
Aspergillus candidus
NCBI taxonomy Id: 41067
Other names: A. candidus, CBS 566.65
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.