node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GFO_2250 | gltA | GFO_2250 | GFO_2807 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | Class I citrate synthase; Belongs to the citrate synthase family. | 0.685 |
GFO_2250 | mutB | GFO_2250 | GFO_0809 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | methylmalonyl-CoA mutase large subunit. | 0.825 |
GFO_2250 | sdhA | GFO_2250 | GFO_3149 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | Succinate dehydrogenase flavoprotein subunit. | 0.620 |
GFO_2250 | sdhB | GFO_2250 | GFO_3150 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | Succinate dehydrogenase iron-sulfur protein. | 0.664 |
GFO_2250 | sucA | GFO_2250 | GFO_3083 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | 2-oxoglutarate dehydrogenase E1 component. | 0.999 |
GFO_2250 | sucB | GFO_2250 | GFO_3082 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.920 |
GFO_2250 | sucC | GFO_2250 | GFO_0752 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.970 |
GFO_2250 | sucD | GFO_2250 | GFO_1768 | Lipoamide acyltransferase component of 2-oxoacid dehydrogenase complex. | succinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.966 |
GFO_2888 | aceF | GFO_2888 | GFO_1680 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.922 |
GFO_2888 | gltA | GFO_2888 | GFO_2807 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Class I citrate synthase; Belongs to the citrate synthase family. | 0.967 |
GFO_2888 | mutB | GFO_2888 | GFO_0809 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | methylmalonyl-CoA mutase large subunit. | 0.825 |
GFO_2888 | sdhA | GFO_2888 | GFO_3149 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase flavoprotein subunit. | 0.620 |
GFO_2888 | sdhB | GFO_2888 | GFO_3150 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase iron-sulfur protein. | 0.664 |
GFO_2888 | sucA | GFO_2888 | GFO_3083 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component. | 0.963 |
GFO_2888 | sucC | GFO_2888 | GFO_0752 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.940 |
GFO_2888 | sucD | GFO_2888 | GFO_1768 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.929 |
aceF | GFO_2888 | GFO_1680 | GFO_2888 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.922 |
aceF | gltA | GFO_1680 | GFO_2807 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | Class I citrate synthase; Belongs to the citrate synthase family. | 0.967 |
aceF | mutB | GFO_1680 | GFO_0809 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | methylmalonyl-CoA mutase large subunit. | 0.825 |
aceF | sdhA | GFO_1680 | GFO_3149 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | Succinate dehydrogenase flavoprotein subunit. | 0.620 |