STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFO_0840Aldo/keto reductase family protein. (280 aa)    
Predicted Functional Partners:
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
     
 0.910
GFO_0312
D-isomer-specific 2-hydroxyacid dehydrogenase family protein.
    
 0.909
GFO_0309
Serine/threonine dehydratase.
  
 
 0.808
ilvA
Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.808
GFO_1974
Secreted flavin-containing amine oxidoreductase.
   
 
 0.805
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
  0.803
GFO_2084
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.800
GFO_1041
Trehalose 6-phosphate synthase/phosphatase.
   
  
 0.705
GFO_0332
Methionine synthase N-terminal domain-like protein.
  
 0.563
Your Current Organism:
Gramella forsetii
NCBI taxonomy Id: 411154
Other names: Cytophaga sp. KT0803, G. forsetii KT0803, Gramella forsetii KT0803, Gramella forsetii str. KT0803, Gramella forsetii strain KT0803
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