Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GFO_0959Crp family transcriptional regulator protein. (210 aa)    
Predicted Functional Partners:
GFO_0960
Membrane protein containing DUF81.
 
     0.672
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.588
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.581
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.572
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.552
GFO_0649
Conserved hypothetical protein.
    
   0.543
GFO_0958
NADP-dependent aldehyde dehydrogenase.
   
   0.498
oxyR
Redox-sensitive transcriptional activator; Belongs to the LysR transcriptional regulatory family.
   
 
 0.477
GFO_0018
Secreted protein containing adenylate/guanylate cyclase catalytic domain; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 
 0.420
GFO_0037
Membrane protein containing adenylate/guanylate cyclase catalytic domain.
  
 
 0.420
Your Current Organism:
Gramella forsetii
NCBI taxonomy Id: 411154
Other names: Cytophaga sp. KT0803, G. forsetii KT0803, Gramella forsetii KT0803, Gramella forsetii str. KT0803, Gramella forsetii strain KT0803
Server load: low (26%) [HD]