| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GFO_0219 | GFO_0270 | GFO_0219 | GFO_0270 | OMPP1/FadL/TodX family outer membrane protein transport protein. | HTH_3 family transcriptional regulator protein. | 0.648 |
| GFO_0219 | GFO_1104 | GFO_0219 | GFO_1104 | OMPP1/FadL/TodX family outer membrane protein transport protein. | Conserved hypothetical protein, secreted. | 0.680 |
| GFO_0270 | GFO_0219 | GFO_0270 | GFO_0219 | HTH_3 family transcriptional regulator protein. | OMPP1/FadL/TodX family outer membrane protein transport protein. | 0.648 |
| GFO_0270 | GFO_1104 | GFO_0270 | GFO_1104 | HTH_3 family transcriptional regulator protein. | Conserved hypothetical protein, secreted. | 0.407 |
| GFO_1100 | GFO_1103 | GFO_1100 | GFO_1103 | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease BN. | 0.578 |
| GFO_1100 | GFO_1104 | GFO_1100 | GFO_1104 | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Conserved hypothetical protein, secreted. | 0.499 |
| GFO_1100 | GFO_1105 | GFO_1100 | GFO_1105 | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Conserved hypothetical protein, secreted. | 0.516 |
| GFO_1100 | nadC | GFO_1100 | GFO_1102 | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.582 |
| GFO_1100 | priA | GFO_1100 | GFO_1106 | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Primosomal protein N' (replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.507 |
| GFO_1100 | rlmH | GFO_1100 | GFO_1101 | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Protein containing DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.798 |
| GFO_1103 | GFO_1100 | GFO_1103 | GFO_1100 | Ribonuclease BN. | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.578 |
| GFO_1103 | GFO_1104 | GFO_1103 | GFO_1104 | Ribonuclease BN. | Conserved hypothetical protein, secreted. | 0.698 |
| GFO_1103 | GFO_1105 | GFO_1103 | GFO_1105 | Ribonuclease BN. | Conserved hypothetical protein, secreted. | 0.715 |
| GFO_1103 | nadC | GFO_1103 | GFO_1102 | Ribonuclease BN. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.797 |
| GFO_1103 | priA | GFO_1103 | GFO_1106 | Ribonuclease BN. | Primosomal protein N' (replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.586 |
| GFO_1103 | rlmH | GFO_1103 | GFO_1101 | Ribonuclease BN. | Protein containing DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.606 |
| GFO_1104 | GFO_0219 | GFO_1104 | GFO_0219 | Conserved hypothetical protein, secreted. | OMPP1/FadL/TodX family outer membrane protein transport protein. | 0.680 |
| GFO_1104 | GFO_0270 | GFO_1104 | GFO_0270 | Conserved hypothetical protein, secreted. | HTH_3 family transcriptional regulator protein. | 0.407 |
| GFO_1104 | GFO_1100 | GFO_1104 | GFO_1100 | Conserved hypothetical protein, secreted. | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.499 |
| GFO_1104 | GFO_1103 | GFO_1104 | GFO_1103 | Conserved hypothetical protein, secreted. | Ribonuclease BN. | 0.698 |