| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GFO_1740 | GFO_1742 | GFO_1740 | GFO_1742 | Conserved hypothetical protein. | Succinylglutamate desuccinylase/aspartoacylase family protein. | 0.936 |
| GFO_1740 | gshB | GFO_1740 | GFO_1741 | Conserved hypothetical protein. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.949 |
| GFO_1742 | GFO_1740 | GFO_1742 | GFO_1740 | Succinylglutamate desuccinylase/aspartoacylase family protein. | Conserved hypothetical protein. | 0.936 |
| GFO_1742 | gshB | GFO_1742 | GFO_1741 | Succinylglutamate desuccinylase/aspartoacylase family protein. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.926 |
| GFO_2330 | ggt | GFO_2330 | GFO_1955 | Secreted aminopeptidase. | Gamma-glutamyltranspeptidase. | 0.905 |
| GFO_2330 | glyA | GFO_2330 | GFO_2262 | Secreted aminopeptidase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.833 |
| GFO_2330 | gshB | GFO_2330 | GFO_1741 | Secreted aminopeptidase. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.900 |
| GFO_2330 | pepD | GFO_2330 | GFO_0785 | Secreted aminopeptidase. | Aminoacyl-histidine dipeptidase. | 0.906 |
| ggt | GFO_2330 | GFO_1955 | GFO_2330 | Gamma-glutamyltranspeptidase. | Secreted aminopeptidase. | 0.905 |
| ggt | gor | GFO_1955 | GFO_1323 | Gamma-glutamyltranspeptidase. | Glutathione reductase. | 0.907 |
| ggt | gor-2 | GFO_1955 | GFO_3156 | Gamma-glutamyltranspeptidase. | Glutathione reductase. | 0.907 |
| ggt | gshB | GFO_1955 | GFO_1741 | Gamma-glutamyltranspeptidase. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.910 |
| ggt | merA | GFO_1955 | GFO_1127 | Gamma-glutamyltranspeptidase. | Mercuric reductase. | 0.907 |
| ggt | pepD | GFO_1955 | GFO_0785 | Gamma-glutamyltranspeptidase. | Aminoacyl-histidine dipeptidase. | 0.909 |
| glyA | GFO_2330 | GFO_2262 | GFO_2330 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Secreted aminopeptidase. | 0.833 |
| glyA | gor | GFO_2262 | GFO_1323 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutathione reductase. | 0.421 |
| glyA | gor-2 | GFO_2262 | GFO_3156 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutathione reductase. | 0.401 |
| glyA | gshB | GFO_2262 | GFO_1741 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. | 0.805 |
| glyA | merA | GFO_2262 | GFO_1127 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Mercuric reductase. | 0.411 |
| glyA | pepD | GFO_2262 | GFO_0785 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminoacyl-histidine dipeptidase. | 0.850 |