node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GFO_0976 | GFO_3401 | GFO_0976 | GFO_3401 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | 0.819 |
GFO_0976 | accC | GFO_0976 | GFO_3345 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.989 |
GFO_0976 | acsA | GFO_0976 | GFO_1907 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.924 |
GFO_0976 | leuA | GFO_0976 | GFO_2095 | acyl-CoA carboxylase carboxyl transferase beta subunit. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.415 |
GFO_0976 | pyc | GFO_0976 | GFO_2678 | acyl-CoA carboxylase carboxyl transferase beta subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.832 |
GFO_1326 | accC | GFO_1326 | GFO_3345 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.925 |
GFO_1326 | accD | GFO_1326 | GFO_0383 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | 0.911 |
GFO_1326 | aceF | GFO_1326 | GFO_1680 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.909 |
GFO_1326 | acsA | GFO_1326 | GFO_1907 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.972 |
GFO_1326 | atoB | GFO_1326 | GFO_1507 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.927 |
GFO_1326 | gltA | GFO_1326 | GFO_2807 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Class I citrate synthase; Belongs to the citrate synthase family. | 0.936 |
GFO_1326 | leuA | GFO_1326 | GFO_2095 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.929 |
GFO_1326 | pyc | GFO_1326 | GFO_2678 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.482 |
GFO_3401 | GFO_0976 | GFO_3401 | GFO_0976 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.819 |
GFO_3401 | acsA | GFO_3401 | GFO_1907 | Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.938 |
accC | GFO_0976 | GFO_3345 | GFO_0976 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acyl-CoA carboxylase carboxyl transferase beta subunit. | 0.989 |
accC | GFO_1326 | GFO_3345 | GFO_1326 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.925 |
accC | accD | GFO_3345 | GFO_0383 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | 0.995 |
accC | aceF | GFO_3345 | GFO_1680 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.916 |
accC | acsA | GFO_3345 | GFO_1907 | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.920 |