STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (438 aa)    
Predicted Functional Partners:
GFO_0332
Methionine synthase N-terminal domain-like protein.
  
 
 0.928
GFO_0333
5-methyltetrahydrofolate:homocysteine methyltransferase-cobalamin binding domain; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.926
GFO_1794
Cysteine synthase/cystathionine beta-synthase.
  
 0.925
GFO_2397
Cysteine synthase/cystathionine beta-synthase.
  
 0.925
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.917
GFO_0761
Cys/Met metabolism pyridoxal-phosphate-dependent enzyme.
  
 0.917
metC
Cys/Met metabolism pyridoxal-phosphate-dependent enzyme.
  
 0.917
GFO_0316
O-acetylhomoserine/O-acetylserine sulfhydrylase.
     
 0.916
thrA
Bifunctional aspartokinase/homoserine dehydrogenase.
   
 
 0.840
GFO_0309
Serine/threonine dehydratase.
  
 
 0.824
Your Current Organism:
Gramella forsetii
NCBI taxonomy Id: 411154
Other names: Cytophaga sp. KT0803, G. forsetii KT0803, Gramella forsetii KT0803, Gramella forsetii str. KT0803, Gramella forsetii strain KT0803
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.