STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFO_3234methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (156 aa)    
Predicted Functional Partners:
queG
Protein containing DUF1730 and [4Fe-4S] binding domain; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.
      0.905
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      0.844
GFO_3233
Membrane protein containing DUF21 and CBS domains.
       0.817
GFO_3235
Secreted beta-lactamase family protein.
       0.728
GFO_3236
Conserved hypothetical protein.
       0.728
GFO_3040
DNA-3-methyladenine glycosylase.
      0.709
GFO_3237
Hypothetical protein.
       0.494
GFO_3232
Hypothetical protein.
       0.491
mutY
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
 
   
 0.472
rpoD
RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   0.428
Your Current Organism:
Gramella forsetii
NCBI taxonomy Id: 411154
Other names: Cytophaga sp. KT0803, G. forsetii KT0803, Gramella forsetii KT0803, Gramella forsetii str. KT0803, Gramella forsetii strain KT0803
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.