node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GFO_0643 | GFO_1620 | GFO_0643 | GFO_1620 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Phosphorylase family protein. | 0.901 |
GFO_0643 | GFO_3484 | GFO_0643 | GFO_3484 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Cytidine/deoxycytidylate deaminase family protein. | 0.902 |
GFO_0643 | cdd | GFO_0643 | GFO_2890 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.903 |
GFO_0643 | deoD | GFO_0643 | GFO_1416 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Purine nucleoside phosphorylase DeoD. | 0.900 |
GFO_0643 | dut | GFO_0643 | GFO_3262 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
GFO_0643 | punA | GFO_0643 | GFO_3610 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Purine nucleoside phosphorylase PunA; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.909 |
GFO_0643 | surE | GFO_0643 | GFO_2964 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.907 |
GFO_0643 | tdk | GFO_0643 | GFO_3354 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidine kinase. | 0.915 |
GFO_0643 | thyA | GFO_0643 | GFO_0288 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.903 |
GFO_0643 | ushA-2 | GFO_0643 | GFO_1282 | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.927 |
GFO_1620 | GFO_0643 | GFO_1620 | GFO_0643 | Phosphorylase family protein. | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.901 |
GFO_1620 | cdd | GFO_1620 | GFO_2890 | Phosphorylase family protein. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.981 |
GFO_1620 | deoD | GFO_1620 | GFO_1416 | Phosphorylase family protein. | Purine nucleoside phosphorylase DeoD. | 0.975 |
GFO_1620 | punA | GFO_1620 | GFO_3610 | Phosphorylase family protein. | Purine nucleoside phosphorylase PunA; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.925 |
GFO_1620 | surE | GFO_1620 | GFO_2964 | Phosphorylase family protein. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.906 |
GFO_1620 | tdk | GFO_1620 | GFO_3354 | Phosphorylase family protein. | Thymidine kinase. | 0.915 |
GFO_1620 | ushA-2 | GFO_1620 | GFO_1282 | Phosphorylase family protein. | Periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.901 |
GFO_3484 | GFO_0643 | GFO_3484 | GFO_0643 | Cytidine/deoxycytidylate deaminase family protein. | Secreted or periplasmic 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.902 |
GFO_3484 | dut | GFO_3484 | GFO_3262 | Cytidine/deoxycytidylate deaminase family protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.940 |
GFO_3484 | surE | GFO_3484 | GFO_2964 | Cytidine/deoxycytidylate deaminase family protein. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |