STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GFO_3592Conserved hypothetical protein, membrane or secreted. (167 aa)    
Predicted Functional Partners:
GFO_3593
Conserved hypothetical protein.
 
    0.863
secG
Membrane protein containing preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
       0.822
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.753
GFO_0794
Protein containing tetratricopeptide repeats.
  
     0.751
GFO_0145
Conserved hypothetical protein, membrane.
  
     0.725
GFO_3340
Protein containing DUF177.
  
     0.717
GFO_0385
Conserved hypothetical protein, secreted.
  
     0.703
lepB
Signal peptidase I; Belongs to the peptidase S26 family.
  
     0.703
GFO_0804
Conserved hypothetical protein, secreted.
  
    0.699
GFO_3531
Conserved hypothetical protein, secreted.
  
     0.695
Your Current Organism:
Gramella forsetii
NCBI taxonomy Id: 411154
Other names: Cytophaga sp. KT0803, G. forsetii KT0803, Gramella forsetii KT0803, Gramella forsetii str. KT0803, Gramella forsetii strain KT0803
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.