STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M1CZN1_SOLTUUncharacterized protein. (259 aa)    
Predicted Functional Partners:
M0ZKN5_SOLTU
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.883
M0ZJD1_SOLTU
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
  
  
 0.762
M0ZKM4_SOLTU
Uncharacterized protein.
   
 
 0.751
M1CZM1_SOLTU
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.703
M1D378_SOLTU
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.686
M1B4R8_SOLTU
Uncharacterized protein.
   
 
 0.672
M1CYD8_SOLTU
Uncharacterized protein.
   
 
 0.672
M1B113_SOLTU
Cnd3 domain-containing protein.
   
 
 0.640
M0ZLH9_SOLTU
Structural maintenance of chromosomes protein.
   
 
 0.607
M1A8E0_SOLTU
Uncharacterized protein.
   
 
 0.607
Your Current Organism:
Solanum tuberosum
NCBI taxonomy Id: 4113
Other names: S. tuberosum, Solanum tuberosum L., Solanum tuberosum subsp. tuberosum, potato, potatoes
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