STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RROP1Apyrase; Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates. (454 aa)    
Predicted Functional Partners:
M1BKN3_SOLTU
Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family.
  
 
0.934
M1AWA7_SOLTU
Uncharacterized protein.
   
 
 0.916
M1AI56_SOLTU
Glutamine amidotransferase type-1 domain-containing protein.
   
 
  0.915
M1B2B1_SOLTU
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
   
 
  0.915
M0ZRR0_SOLTU
SurE domain-containing protein.
     
 0.911
M1A159_SOLTU
SurE domain-containing protein.
     
 0.911
PURA
Adenylosuccinate synthetase, chloroplastic; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
     
 0.911
PURA-2
Adenylosuccinate synthetase, chloroplastic; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
     
 0.911
M1CWA0_SOLTU
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.911
M1AEK1_SOLTU
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
   
 
  0.908
Your Current Organism:
Solanum tuberosum
NCBI taxonomy Id: 4113
Other names: S. tuberosum, Solanum tuberosum L., Solanum tuberosum subsp. tuberosum, potato, potatoes
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