Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR48474.1Sugar-binding domain protein; KEGG: msm:MSMEG_3095 7.8e-05 D-ribose-binding periplasmic protein; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98. (305 aa)    
Predicted Functional Partners:
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.749
EDR48472.1
Hypothetical protein; KEGG: sth:STH773 5.9e-07 ribose ABC transporter ATP-binding protein K02056; COG: COG1879 ABC-type sugar transport system, periplasmic component.
 
    0.653
EDR48473.1
Hypothetical protein; KEGG: sth:STH773 1.3e-07 ribose ABC transporter ATP-binding protein K02056; COG: COG1879 ABC-type sugar transport system, periplasmic component; Psort location: Extracellular, score: 8.82.
  
    0.594
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.558
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.524
EDR47321.1
KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators.
  
     0.521
EDR48464.1
Phosphocarrier, HPr family; KEGG: btl:BALH_3665 2.4e-11 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 9.98.
    
 
 0.503
crh
HPr-like protein crh; KEGG: btl:BALH_4643 1.3e-10 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 9.65.
    
 
 0.503
ptsH
Phosphocarrier protein HPr; KEGG: btl:BALH_3665 1.4e-15 ptsH; phosphocarrier protein HPr K00889; COG: COG1925 Phosphotransferase system, HPr-related proteins; Psort location: Cytoplasmic, score: 10.00.
    
 
 0.503
EDR46763.1
Hypothetical protein; COG: COG1609 Transcriptional regulators.
  
     0.501
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.