STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR48474.1Sugar-binding domain protein; KEGG: msm:MSMEG_3095 7.8e-05 D-ribose-binding periplasmic protein; COG: COG1609 Transcriptional regulators; Psort location: Cytoplasmic, score: 9.98. (305 aa)    
Predicted Functional Partners:
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 0.750
EDR48472.1
Hypothetical protein; KEGG: sth:STH773 5.9e-07 ribose ABC transporter ATP-binding protein K02056; COG: COG1879 ABC-type sugar transport system, periplasmic component.
 
 
  0.649
EDR48473.1
Hypothetical protein; KEGG: sth:STH773 1.3e-07 ribose ABC transporter ATP-binding protein K02056; COG: COG1879 ABC-type sugar transport system, periplasmic component; Psort location: Extracellular, score: 8.82.
  
 
  0.589
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.547
EDR47321.1
KEGG: spj:MGAS2096_Spy0983 0.0052 transcriptional regulator, GntR family / aminotransferase class-I; COG: COG1609 Transcriptional regulators.
  
     0.521
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.515
EDR47543.1
Branched-chain amino acid ABC transporter, permease protein; KEGG: msm:MSMEG_4171 7.2e-58 ribose transport system permease protein RbsC; COG: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
  0.504
EDR46763.1
Hypothetical protein; COG: COG1609 Transcriptional regulators.
  
     0.501
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.493
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
   0.493
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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