Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
EDR48485.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 2.5e-55 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (470 aa)    
Predicted Functional Partners:
EDR48484.1
Response regulator receiver domain protein; KEGG: ava:Ava_3369 2.6e-46 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.945
EDR45928.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 8.1e-43 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.812
EDR48486.1
PDZ/DHR/GLGF domain protein; KEGG: chy:CHY_0655 4.7e-21 htrA; serine protease Do; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.803
EDR45879.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 6.4e-50 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.797
EDR47326.1
Response regulator receiver domain protein; KEGG: eci:UTI89_C0420 4.5e-42 phoB; positive response regulator for pho regulon K07657; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.783
EDR47506.1
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 8.3e-41 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.773
EDR47552.1
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 1.2e-46 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.769
EDR45681.1
Response regulator receiver domain protein; KEGG: ava:Ava_3369 6.7e-39 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.65.
 
 
 0.760
EDR46109.1
KEGG: rha:RHA1_ro05622 2.2e-33 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 0.742
EDR46694.1
Response regulator receiver domain protein; KEGG: ava:Ava_3369 1.5e-34 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.733
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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