Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDR48487.1HDIG domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87. (313 aa)    
Predicted Functional Partners:
EDR48486.1
PDZ/DHR/GLGF domain protein; KEGG: chy:CHY_0655 4.7e-21 htrA; serine protease Do; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Psort location: Cytoplasmic, score: 8.87.
       0.617
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
     0.600
rumA
23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: bha:BH0687 3.0e-123 RNA methyltransferase K00599; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.551
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.519
EDR48489.1
Hypothetical protein.
       0.519
EDR46603.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
  
     0.486
EDR48485.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00191 2.5e-55 sensory transduction histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
       0.455
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
    0.449
rny
YmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay.
  
   
 0.444
EDR47701.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
    0.417
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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