Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
rumA23S rRNA (uracil-5-)-methyltransferase RumA; KEGG: bha:BH0687 3.0e-123 RNA methyltransferase K00599; COG: COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (467 aa)    
Predicted Functional Partners:
EDR48489.1
Hypothetical protein.
       0.773
EDR48487.1
HDIG domain protein; COG: COG3481 Predicted HD-superfamily hydrolase; Psort location: Cytoplasmic, score: 8.87.
       0.551
EDR48490.1
Hypothetical protein; KEGG: cpf:CPF_1212 2.2e-08 kdpC; K+-transporting ATPase, C subunit K01545.
       0.542
rsmI
S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
  
 0.530
EDR48486.1
PDZ/DHR/GLGF domain protein; KEGG: chy:CHY_0655 4.7e-21 htrA; serine protease Do; COG: COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Psort location: Cytoplasmic, score: 8.87.
  
    0.470
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.414
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.414
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.410
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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