Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDR48502.1Nitroreductase family protein; KEGG: afu:AF0131 5.4e-14 NAD(P)H-flavin oxidoreductase, putative; COG: COG0778 Nitroreductase. (217 aa)    
Predicted Functional Partners:
EDR46358.1
Nitroreductase family protein; KEGG: tma:TM0383 2.9e-31 NADH oxidoreductase, putative; COG: COG0778 Nitroreductase; Psort location: Cytoplasmic, score: 8.87.
  
     0.744
hydF
Hydrogenase maturation GTPase HydF; KEGG: hpa:HPAG1_1378 4.6e-14 putative thiophene/furan oxidation protein K00058; COG: COG1160 Predicted GTPases; Psort location: Cytoplasmic, score: 8.87.
       0.624
EDR47723.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.556
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.537
EDR47264.1
Glyoxalase family protein; KEGG: fnu:FN0356 4.7e-38 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases.
  
    0.523
EDR47722.1
Hypothetical protein; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.515
hydE
Iron-only hydrogenase maturation rSAM protein HydE; KEGG: bth:BT1835 1.2e-103 biotin synthetase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
       0.438
EDR46567.1
CAAX amino terminal protease family protein; COG: COG1668 ABC-type Na+ efflux pump, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.434
EDR48060.1
AMP-binding enzyme; KEGG: bca:BCE_0965 4.7e-70 AMP-binding protein K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: Cytoplasmic, score: 9.98.
   
   0.414
EDR45604.1
AMP-binding enzyme; KEGG: bha:BH3104 1.2e-57 long-chain fatty-acid-CoA ligase K01897; COG: COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; Psort location: CytoplasmicMembrane, score: 9.49.
   
   0.414
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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